Klyucharov I.V., Kamalova R.R., Shulaev A.V., Zhaboeva S.L. Speaker: Klyucharov I.V. – MD, PhD, Associate Professor of the Department of Obstetrics and Gynecology, Kazan State Medical University, Ministry of Health of the Russian Federation Kamalova R.R. – Resident Physician of Obstetrics and Gynecology, Kazan State Medical University, Ministry of Health of the Russian Federation Shulaev A.V. – MD, Professor, Vice-Rector of Kazan State Medical University, Ministry of Health of the Russian Federation Zhaboeva S.L. – MD, Associate Professor, Kazan State Medical University, Ministry of Health of the Russian Federation, Director of the Clinic of Youth and Beauty SL, LLC. Institutions: Kazan State Medical University, Ministry of Health of the Russian Federation, Clinic of Youth and Beauty SL, LLC. E-mail: klyucharoff@yandex.ru [ mailto:klyucharoff@yandex.ru ] , klyucharovi@outlook.com [ mailto:klyucharovi@outlook.com ] tel: +7 (917) 2824474 It is assumed that minimal trauma to the endometrium during removal of a pathological formation of the uterine cavity or endometrial biopsy increases the chances of attachment of a fertilized egg. Objective of the study: Assessment of the pregnancy rate after office hysteroscopy. Assessment of the level of pain during office hysteroscopy at the diagnostic and surgical stages, in comparison with the level of pain during menstruation. Assessment of satisfaction with the operation. Intervention: office hysteroscopy, removal of intrauterine pathology, endometrial biopsy, tubal recanalization. Equipment and parameters: hysteroscope d 4.8x3.8 mm, pressure 50-70 mm Hg. St., one physician, one clinic. Study contingent: 101 out of 120 patients were interviewed, 19 patients were excluded from the study. Study groups: 1 - did not plan pregnancy (43 people, 42.6%), 2 - planned pregnancy (58 people, 57.4%), within which: 2a - planned pregnancy naturally (42 people, 72.4%), 2b - had indications for ART (16 people, 27.6%). Research method: retrospective standardized telephone interview 6 months or more after hysteroscopy. The interview was conducted by a gynecologist who had no previous contact with the study participants. Assessment of pain sensations using a 10-point VAS during menstruation, during the diagnostic stage and during the operative stage of hysteroscopy. Satisfaction assessment using a 5-point scale. Statistical processing of the results using the Statistica 10 program. Results of the study: The groups were comparable in age, intrauterine pathology was represented mainly by endometrial polyps, less often by adhesions and submucous fibroids. VAS of pain during menstruation in group 1 was 2.53±0.84, group 2 was 3.67±0.34, group 2a was 3.5±0.39, group 2b was 4.12±0.67. VAS of pain at the diagnostic stage was 1.74±0.32; 1.81±0.24; 1.67±0.25; 2.18±0.6, respectively. VAS of pain at the surgical stage was 3.07±0.45; 3.65±0.35; 3.69±0.41; 3.56±0.62, respectively. No statistically significant developments were found (p> 0.05). Statistically significant differences were found within the groups in the level of pain between menstruation, diagnostic and surgical stages (p<0.05). In group 2a, 25 (60.0%) of 42 patients became pregnant, in 2b, 4 (25%) of 16 became pregnant. The satisfaction level was in group 1 - 4.79±0.1; group 2 - 4.87±0.05; group 2a - 4.85±0.07; group 2b - 4.93±0.06. No statistically significant developments were found (p> 0.05). Conclusions: Office hysteroscopy is well tolerated by patients. The level of pain experienced by women during menstruation is significantly higher than during the diagnostic and surgical stages of office hysteroscopy. Office hysteroscopy, accompanied by removal of the pathological formation, endometrial biopsy and recanalization of the tubal orifices, increases the chances of becoming pregnant in patients who are not indicated for ART but have not become pregnant for a long time due to the presence of certain pathologies of the uterine cavity.