A.E. Ataliev, R.M. Madaminov, V.V. Stupin, and B.K. Rakhimov. Tashkent. Advances in modern laparoscopic cholecystectomy techniques, including those using M.I. Prudkov's method, do not diminish the relevance and necessity of traditional gallbladder interventions. An analysis of the results of 1,060 surgical interventions on the gallbladder and extrahepatic bile ducts revealed that wound suppuration, eventration, postoperative hernia formation, and abdominal wall deformation are common postoperative complications when using the Kocher, Fedorov, upper midline laparotomy, and pararectal incisions. Achieving optimal surgical conditions and maximizing tissue sparing are the goals surgeons strive to achieve when choosing a surgical approach. For chronic and uncomplicated acute cholecystitis, it is advisable to use minimally invasive small abdominal wall incisions in the right hypochondrium. We widely use the intermuscular mini-approach. A skin incision is made in the right hypochondrium parallel to the costal margin, 3-4 cm from its edge, and 6-7 cm long. The center of the incision should be aligned with the ultrasound-diagnosed projection of the gallbladder neck. The external and internal oblique and transverse muscles are dissected longitudinally. If necessary, to increase the surgical angle, the outer edge of the rectus abdominis sheath is partially dissected, thereby allowing for its retraction. The advantage of this method is the preservation of the integrity of muscle fibers, intercostal nerves, and vessels. This is in contrast to the Kocher and Fedorov approaches, which require transection of one to six intercostal nerves and vessels. Since 1995, the described approach has been used in 292 patients with gallbladder disease, aged 18 to 85 years. Of these, 227 were women and 65 were men. Chronic cholecystitis accounted for 109 cases, while acute cholecystitis accounted for 183. A total of 270 cholecystectomies were performed "from the neck," with 22 cases combined with Halsted-Pikovsky drainage of the common bile duct. In 15 cases, the intermuscular mini-approach had to be expanded due to bleeding from the gallbladder bed or cystic artery, or anatomical complications in the hepatobiliary area. Clinical observations during surgery, the course of the wound healing, and favorable long-term results allow us to recommend the intermuscular mini-approach for gallbladder surgery.