M.Yu. Korkmazov Chelyabinsk State Medical Academy It is known that the treatment of chronic polypous rhinosinusitis is an extremely complex process. This is understandable given the polyetiology of this disease, the characteristics of pathophysiological processes, clinical course, etc. In our practice, for over 4.5 years, we have introduced the method of bioresonance therapy for the purpose of diagnosis and rehabilitation of the above-mentioned conditions. To achieve the most positive results, we have always adhered to the following goal: determining the factors of the effectiveness of treatment with the bioresonance method, as well as creating an algorithm for successful therapy, in a comprehensive approach to the rehabilitation of patients with polypous rhinosinusitis. Determining factors: - oscillation characteristics or oscillation type. Coincidence of the oscillation spectrum of the normal and damaged mucous membrane always increases the likelihood of the resonance effect; - frequency and number of oscillations in a limited period of time. For resonance to occur in polypous tissue, the frequency of the applied vibrations must match the frequency of the polypous tissue itself and the normal nasal mucosa; the amplitude and pitch of the vibrations are the same. The greater the amplitude, the higher the probability of resonance. If these aspects of the electromagnetic fields of the normal nasal mucosa and the polypous tissue are somewhat similar, then resonance between them is possible. The more similar they are, the more likely resonance is; otherwise, resonance is virtually impossible. Any therapy, to be successful, must meet several fundamental principles and adhere to the following criteria: 1. The therapeutic effect must always be holistic. This means that any organism is a complex self-regulating system, and any influence on such a system and process involves anatomical, functional, physiological, and pathological interrelations. 2. Therapeutic measures must be causal. Therapeutic measures should not be symptomatic, eliminating only the symptom. This approach will never produce the desired effect, and therefore it is necessary to influence a higher, i.e., causal, mechanism to achieve the desired positive outcome. 3. The treatment must be individualized. The higher the level of our bioresonance treatment (polypous tissue and nasal mucosa), the more multifaceted and, therefore, individualized the treatment must be. Any therapy capable of inducing bioresonance is, by definition, always a highly individualized form of therapy. 4. Therapy must be based on the regulatory effect. The patient's condition always depends on the body's own ability to regulate processes. Recovery can only be achieved by restoring the body's own regulatory system, which is the main goal of bioresonance therapy. Correctly obtained initial data from polypous tissue and intact nasal mucosa, careful processing, adequate reproduction with the creation of inversion, etc. can satisfy all these requirements. It follows that bioresonance therapy should be, and always is, a holistic, causal, individualized, and regulating therapy. Only by adhering to the above-mentioned key criteria, taking into account the aforementioned factors, can the most positive and lasting results be achieved.